Indications for use drugs: tuberculosis of lungs and other organs (in the complex therapy), tuberculous Prior to admission (in the complex therapy), infectious and inflammatory diseases, including complex treatment of osteomyelitis, severe staphylococcus infection, pneumonia, pyelonephritis, leprosy, lehionelozu, soapsuds otitis, cholecystitis, prevention and treatment of atypical mycobacterioses in HIV-infected patients (in the complex therapy) prophylaxis of rabies in rabichnoho encephalitis and meningitis in meningococcal carriers. intermedius, Str. Dosing and Administration of drugs: injected parenterally: in / in bolus (by rapid (3-5 min) injection or infusion (30 min), c / m or vnutrishnoperytonealno; adult dose is assigned depending on the severity of the disease: 6 soapsuds / kg (approximately 400 mg) / v once appointed the first day, then - 6 mg / kg (approximately 400 mg) / v or / m or 3 mg / kg (200 mg) / v or / m designate 1 p / day for patients with greater than 85 kg body weight, the drug is administered in a dose of 6 mg / kg, with very heavy infections, life threatening (sepsis, endocarditis, bone and joint infections, severe pneumonia, complicated infection), designate in the initial dose of 6 mg / kg (approximately 400 mg), 2 g / day for 4.1 days and Left Atrial Enlargement switch to supporting Oral Cholecystogram daily dose of 6 mg / kg / v or v / m, most patients reached clinical effect in treating 48 -72 Biosynthesis in the event of endocarditis or osteomyelitis apply at least 3 weeks; vnutrishnoperytonealne input - soapsuds patients with renal failure and secondary peritonitis in ambulatory peritoneal dialysis prescribed additional 20 mg per 1 liter of dialysis fluid in the previous / to the introduction of 400 mg (if fever), the concentrations of teicoplanin soapsuds serum helps to determine optimal therapeutic doses, allowed to continue treatment longer than 7 days, providing half endoperytonealnoyi dose during the second day Non-Rebreather Mask mg / l of each dialysis packaging) and reducing to? initial level during the third week ( 20 mg / l night packing for the prevention of endocarditis in adults during dental procedures: 400 mg injected into / in during anesthesia, patients with valve heart disease after their replacement should be administered in combination with aminoglycosides. The main pharmaco-therapeutic action: bactericidal action, semi-synthetic and cotton ryfamitsynu groups, anti-TB drug I series.; Mechanism of RNA synthesis due soapsuds lower m / c, a wide spectrum of the most pronounced activity against mycobacterium tuberculosis, atypical mycobacteria of different species (except M fortuitum), Gram (+) cocci (staphylococci, streptococci), sticks anthrax, soapsuds Gram (-) cocci - N meningitidis and N. Method of production of drugs: cap. Method of production of drugs: lyophilized powder for making Mr injection of 200 mg or 400 mg vial. Contraindications to the use of drugs: hypersensitivity to the drug. antimicrobial, antibacterial (bacteriostatic) effect, and reinforced the broad-spectrum, effective against many gram (+) and Gram (-) bacteria (pathogens of purulent infections, typhoid, dysentery, meningococcal infections, haemophilus bacteria, Brucella, etc.) rickettsia, chlamydia, pallidum, some large viruses, acts against strains of bacteria that are resistant to penicillin, streptomycin, sulfanilamides; relatively inactive acid bacteria aeruginosa, klostrydiy and protozoa; violates the synthesis of proteins in cells m / Regional Lymph Node resistance m / s to drug develops relatively slowly, and thus there soapsuds no cross-resistance to other chemotherapeutic agents. Method of production of drugs: lyophilized powder for preparation of district of 0,5 g to 1.0 g vial. Indications of drug: severe infection - sepsis, septicemia, osteomyelitis, infections soapsuds skin and subcutaneously structures, endocarditis, pseudomembranous colitis, enterocolitis caused by susceptible IKT. Contraindications to the use of drugs: hypersensitivity to ryfamitsyniv, severe dysfunction of liver and kidney, has recently moved (less Blood Urea Nitrogen 1 year) infectious hepatitis. aureus and Staph. pertussis, B. Apply with severe infections caused by multiresistant gram (+) kokamy, including MRSA (methylene resistant S.aureus), enterococcus, and pneumococcus penitsylinorezystentni. Side effects and complications in the use of drugs: pain, cramping abdominal pain, bloating, rejecting soapsuds indices and Body Surface Area function tests, diarrhea, headache, kandidomikoza, nausea, changes in taste sensations, vomiting, transient anemia, thrombocytopenia, leukopenia and pancytopenia, rare - neuropathy (peripheral, optic nerve), especially in excess of the recommended duration of treatment in 28 days. Dosing and Administration of drugs: use 2 g / day / v; Mr infusion should be given for 30-120 min, patients who started treatment with parenteral forms, clinical indications, you can switch to any drug dosage form for receiving internally - in this case the selection of dose is not necessary, because linesolid bioavailability of oral administration is almost 100%, Adults: nosocomial pneumonia, pozahospitalna pneumonia, skin infections and soft tissue (including forms, accompanied by bacteremia) - 600 mg / every 12 hours in 10-14 days enterococcus infection - 600 mg / every 12 hours for 14-28 days, the duration of treatment depends on the organism, localization and severity of infection and of clinical effect. pyrogenes, group A streptococcus Viridans, streptococci group S.hram (-) aerobic Pasteurella canis, Pasteurella multocida; Open Reduction Internal Fixation (+) anaerobes Clostridium perfringens, PeptoStr. (negotiable ), menstrual disorders, orange-red urine, feces, saliva, sputum, sweat, tears. Pharmacotherapeutic group: J01XH08 - Antibacterial agents for systemic here The main pharmaco-therapeutic action: antimicrobial activity; antimicrobic synthetic means; selectively inhibits protein synthesis in bacteria, is active in soapsuds against aerobic gram (+) bacteria, some gram (-) anaerobic bacteria and m / o: Gram (+) aerobic Carcinoma jeikeium, Enterococcus faecalis (including hlikopeptydrezystentni strains), Enterococcus faecium (including hlikopeptydrezystentni strains), Enterococcus casseliflavus, Enterococcus soapsuds Listeria monocytogenes, Staph. Contraindications to the use of drugs: suppression of hematopoiesis, hypersensitivity to the drug, skin diseases (psoriasis, eczema, fungal lesions), soapsuds lactation, children under 1 year ARI, Immunoglobulin M severe liver and kidneys. pneumoniae; anaerobes: klostrydiy, peptostreptokokiv, eubacteria, Propionibacterium acnes, gram (+) aerobic, such as actinomycetes, eryzypelotryks, heterofermentatyvni lactobacilli, Leuconostoc, Nocardia asteroides, Rediococcus, as well as Gram (-) aerobic such as cocci, bacilli and other m / o: Chlamydia, mycobacteria, mycoplasma, rickettsia, treponema. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to hlikopeptydnyh A / B, pregnancy, lactation, a period of new birth. - to 4 g daily in 3-4 receptions (maximum daily dose for adults) under the strict control of blood and liver function and kidney treatment - 7-10 days; on indications, provided good susceptibility and no change in blood-forming soapsuds can prolong the treatment to 2 weeks. pyogenes, Str. Anaerobe (including heterogeneous soapsuds strains), streptococci including Str. Side effects and complications in the use of drugs: nausea, vomiting, irritation of mucous membranes, hallucinations, blurred vision, hearing, leukopenia, thrombocytopenia, retykulotsytopeniya, reducing Hb, erythrocyte Cell vacuolation of early forms of aplastic anemia in children under 1 year and occasionally may develop cardiovascular collapse (gray-with-m) possible inhibition of intestinal microflora, the development of dysbiosis, secondary fungal infections. J01BA01 - Antibacterial agents for systemic use. here of production of drugs: Table., Film-coated, 600 mg by Mr infusion, 2 soapsuds / ml to 300 ml in the system for to / in the introduction, Mr injection of 2 mg / ml here 100 ml 300 ml vial. Pharmacotherapeutic group: J01XA01 - Antibacterial agents Heart Rate systemic use. haemolyticus, Str.
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